1-ethynylpyrene-modified guanine and cytosine as optical labels for DNA hybridization.
نویسندگان
چکیده
1-ethynylpyrene shows remarkable absorption changes upon DNA hybridization when it is covalently attached to the 8-position of guanine. An absorption band at approximately 420 nm is only present in the duplex, exhibits thermal melting behaviour and provides the basis for a molecular beacon together with 1-ethynylpyrene-modified cytosine.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 3 11 شماره
صفحات -
تاریخ انتشار 2005